Pub. Date : 2009
PMID : 20155627
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Piceatannol inhibits phorbol ester-induced NF-kappa B activation and COX-2 expression in cultured human mammary epithelial cells. | 3,3',4,5'-tetrahydroxystilbene | prostaglandin-endoperoxide synthase 2 | Homo sapiens |
| 2 | In this study, we examined the effect of piceatannol on activation of the nuclear transcription factor NF-kappa B, one of the major transcription factors that regulate proinflammatory COX-2 gene transcription, in human mammary epithelial (MCF-10A) cells treated with the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA). | 3,3',4,5'-tetrahydroxystilbene | prostaglandin-endoperoxide synthase 2 | Homo sapiens |
| 3 | Likewise, TPA-induced expression of COX-2 was abrogated by piceatannol pretreatment. | 3,3',4,5'-tetrahydroxystilbene | prostaglandin-endoperoxide synthase 2 | Homo sapiens |