Title : Spred2 is involved in imatinib-induced cytotoxicity in chronic myeloid leukemia cells.

Pub. Date : 2010 Mar 19

PMID : 20153728






1 Functional Relationships(s)
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1 Together, these data implicate Spred2 in imatinib-induced cytotoxicity in CML cells, possibly by inhibiting the Ras-ERK cascade and the pro-survival signaling molecules SPHK1 and Mcl-1. Imatinib Mesylate MCL1 apoptosis regulator, BCL2 family member Homo sapiens