Title : Critical role for copper/zinc-superoxide dismutase in preventing spontaneous intracerebral hemorrhage during acute and chronic hypertension in mice.

Pub. Date : 2010 Apr

PMID : 20150548






2 Functional Relationships(s)
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1 The goal of this study was to test the hypothesis that changes in superoxide, in genetically altered mice with deletion and overexpression of copper/zinc-superoxide dismutase (SOD1), modulate susceptibility to ICH. Superoxides superoxide dismutase 1, soluble Mus musculus
2 Moreover, levels of superoxide and matrix metalloproteinase-9 were greater in SOD1(-/-) mice than wild-type littermates after induction of ICH. Superoxides superoxide dismutase 1, soluble Mus musculus