Title : Chromosome 17 polysomy without human epidermal growth factor receptor 2 amplification does not predict response to lapatinib plus paclitaxel compared with paclitaxel in metastatic breast cancer.

Pub. Date : 2010 Feb 15

PMID : 20145176






1 Functional Relationships(s)
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1 This hypothesis was examined using the data from a phase III trial that randomized patients with HER2-negative or HER2-untested metastatic breast cancer to first-line therapy with paclitaxel along with either lapatinib or placebo. Paclitaxel erb-b2 receptor tyrosine kinase 2 Homo sapiens