Title : miR-181a and miR-630 regulate cisplatin-induced cancer cell death.

Pub. Date : 2010 Mar 1

PMID : 20145152






1 Functional Relationships(s)
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1 Pre-miR-630 arrested A549 cells in the G0-G1 phase of the cell cycle, correlating with increased levels of the cell cycle inhibitor p27(Kip1) as well as with reduced proliferation rates and resulting in greatly diminished sensitivity of A549 cells to the late S-G2-M cell cycle arrest mediated by CDDP. Cisplatin cyclin dependent kinase inhibitor 1B Homo sapiens