Pub. Date : 2010 Jul
PMID : 20143408
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the biosynthesis of catecholamines released by oxygen-sensitive cells in response to hypoxic conditions. | Oxygen | tyrosine hydroxylase | Rattus norvegicus |
2 | Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the biosynthesis of catecholamines released by oxygen-sensitive cells in response to hypoxic conditions. | Oxygen | tyrosine hydroxylase | Rattus norvegicus |
3 | These results indicate that, under hypoxic conditions, TH (a key factor in systemic adaptation to reduced oxygen availability) is not regulated by HIF-1, the primary modulator of the response to hypoxia, but by the adenosine A(2)A receptor-mediated signalling pathway. | Oxygen | tyrosine hydroxylase | Rattus norvegicus |