Title : Glyoxalase-I is a novel target against Bcr-Abl+ leukemic cells acquiring stem-like characteristics in a hypoxic environment.

Pub. Date : 2010 Jul

PMID : 20139893






1 Functional Relationships(s)
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1 Abl tyrosine kinase inhibitors (TKIs) such as imatinib and dasatinib are ineffective against Bcr-Abl(+) leukemic stem cells. Dasatinib ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens