Title : SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress.

Pub. Date : 2010 Jan 19

PMID : 20129246






1 Functional Relationships(s)
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1 This work demonstrates that SIRT3(-/-) mouse embryonic fibroblasts (MEFs) exhibit abnormal mitochondrial physiology as well as increases in stress-induced superoxide levels and genomic instability. Superoxides sirtuin 3 Mus musculus