Title : Metabolic regulation of neuronal plasticity by the energy sensor AMPK.

Pub. Date : 2010 Feb 1

PMID : 20126541






2 Functional Relationships(s)
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1 Administration of the glycolytic inhibitor 2-deoxy-D-glucose (2DG) or the mitochondrial toxin and anti-Type II Diabetes drug, metformin, or AMP mimetic AICAR results in activation of AMPK, repression of the mTOR pathway and prevents maintenance of Late-Phase LTP (L-LTP). Deoxyglucose protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens
2 Administration of the glycolytic inhibitor 2-deoxy-D-glucose (2DG) or the mitochondrial toxin and anti-Type II Diabetes drug, metformin, or AMP mimetic AICAR results in activation of AMPK, repression of the mTOR pathway and prevents maintenance of Late-Phase LTP (L-LTP). Deoxyglucose protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens