Title : Functional characterization of eight human cytochrome P450 1A2 gene variants by recombinant protein expression.

Pub. Date : 2010 Dec

PMID : 20125119






2 Functional Relationships(s)
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1 Among CYP1A2 variants, out of the heterogeneous set of eight substrates, carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) was the most discriminative compound. 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone cytochrome P450 family 1 subfamily A member 2 Homo sapiens
2 Among CYP1A2 variants, out of the heterogeneous set of eight substrates, carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) was the most discriminative compound. 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone cytochrome P450 family 1 subfamily A member 2 Homo sapiens