Title : The role of endogenous reactive oxygen species in oxymatrine-induced caspase-3-dependent apoptosis in human melanoma A375 cells.

Pub. Date : 2010 Jun

PMID : 20124987






1 Functional Relationships(s)
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1 Furthermore, this small compound resulted in a marked activation of capase-3, caspase-9, and poly (ADP-ribose) polymerase, while caspase-3 inhibitor Z-DEVD-FMK significantly reversed the proapoptotic effect of oxymatrine in A375 cells. oxymatrine poly(ADP-ribose) polymerase 1 Homo sapiens