Title : Role of Akt-dependent up-regulation of hemeoxygenase-1 in resveratrol-mediated attenuation of hepatic injury after trauma hemorrhage.

Pub. Date : 2010 Jul

PMID : 20117814






4 Functional Relationships(s)
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1 Role of Akt-dependent up-regulation of hemeoxygenase-1 in resveratrol-mediated attenuation of hepatic injury after trauma hemorrhage. Resveratrol AKT serine/threonine kinase 1 Rattus norvegicus
2 The aim of this study is to elucidate whether Akt/HO-1 plays any role in resveratrol-mediated attenuation of hepatic injury after trauma hemorrhage. Resveratrol AKT serine/threonine kinase 1 Rattus norvegicus
3 Resveratrol treatment also increased hepatic Akt activation and HO-1 expression as compared with vehicle-treated trauma hemorrhaged rats. Resveratrol AKT serine/threonine kinase 1 Rattus norvegicus
4 CONCLUSION: These findings collectively suggest that the salutary effects of resveratrol administration on attenuation of hepatic injury after trauma hemorrhage are likely mediated via up-regulation of Akt-dependent HO-1 expression. Resveratrol AKT serine/threonine kinase 1 Rattus norvegicus