Pub. Date : 2010 Jul
PMID : 20117814
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Role of Akt-dependent up-regulation of hemeoxygenase-1 in resveratrol-mediated attenuation of hepatic injury after trauma hemorrhage. | Resveratrol | AKT serine/threonine kinase 1 | Rattus norvegicus |
2 | The aim of this study is to elucidate whether Akt/HO-1 plays any role in resveratrol-mediated attenuation of hepatic injury after trauma hemorrhage. | Resveratrol | AKT serine/threonine kinase 1 | Rattus norvegicus |
3 | Resveratrol treatment also increased hepatic Akt activation and HO-1 expression as compared with vehicle-treated trauma hemorrhaged rats. | Resveratrol | AKT serine/threonine kinase 1 | Rattus norvegicus |
4 | CONCLUSION: These findings collectively suggest that the salutary effects of resveratrol administration on attenuation of hepatic injury after trauma hemorrhage are likely mediated via up-regulation of Akt-dependent HO-1 expression. | Resveratrol | AKT serine/threonine kinase 1 | Rattus norvegicus |