Pub. Date : 2010 Jun
PMID : 20107167
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | RESULTS: Zymosan induced the release of IL-6 and IL-8 from corneal fibroblasts without affecting either the release of IL-1beta, IL-12, IP-10, or RANTES or the expression of ICAM-1 or VCAM-1. | Zymosan | interleukin 6 | Homo sapiens |
2 | The zymosan-induced release of IL-6 and IL-8 was attenuated by inhibitors of ERK, p38, JNK, and NF-kappaB signaling. | Zymosan | interleukin 6 | Homo sapiens |
3 | CONCLUSIONS: Zymosan induces the release of IL-6 and IL-8 from human corneal fibroblasts in a manner dependent on MAPK and NF-kappaB signaling pathways. | Zymosan | interleukin 6 | Homo sapiens |