Title : Cyclooxygenase 2 inhibition exacerbates AQP2 and pAQP2 downregulation independently of V2 receptor abundance in the postobstructed kidney.

Pub. Date : 2010 Apr

PMID : 20107111






2 Functional Relationships(s)
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1 Immunoblotting revealed a significant decrease in AQP2 and pS256-AQP2 abundance to 20 and 23% of sham levels in parecoxib-treated BUO rats compared with 40 and 55% of sham levels in saline-treated BUO rats. Diacetyl aquaporin 2 Rattus norvegicus
2 Immunohistochemistry confirmed the exacerbated AQP2 and pS256-AQP2 downregulation in parecoxib-treated BUO rats. Diacetyl aquaporin 2 Rattus norvegicus