Pub. Date : 2010 May
PMID : 20101004
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | It is noteworthy that dosing 12-week-old, asymptomatic hAPP mice over 7 days with pregnenolone-16alpha-carbonitrile to activate the nuclear receptor pregnane X receptor restores P-glycoprotein expression and transport activity in brain capillaries and significantly reduces brain Abeta levels compared with untreated control mice. | Pregnenolone Carbonitrile | amyloid beta (A4) precursor protein | Mus musculus |