Title : Potential role of caveolin-1 in acetaminophen-induced hepatotoxicity.

Pub. Date : 2010 May 15

PMID : 20100502






1 Functional Relationships(s)
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1 Although expression of tumor necrosis factor-alpha, a potent hepatocyte mitogen, was up-regulated in the liver of Cav-1(-/-) mice after acetaminophen, expression of proliferating cell nuclear antigen and survivin, markers of cellular proliferation, were delayed, which may reflect the reduced need for tissue repair. Acetaminophen tumor necrosis factor Mus musculus