Pub. Date : 2010 Apr
PMID : 20099300
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Sorafenib inhibits the shedding of major histocompatibility complex class I-related chain A on hepatocellular carcinoma cells by down-regulating a disintegrin and metalloproteinase 9. | Sorafenib | MHC class I polypeptide-related sequence A | Homo sapiens |
| 2 | Sorafenib treatment resulted in decreased expression of ADAM9, increased expression of membrane-bound MICA expression, and decreased levels of soluble MICA in HCC cells. | Sorafenib | MHC class I polypeptide-related sequence A | Homo sapiens |
| 3 | Sorafenib treatment resulted in decreased expression of ADAM9, increased expression of membrane-bound MICA expression, and decreased levels of soluble MICA in HCC cells. | Sorafenib | MHC class I polypeptide-related sequence A | Homo sapiens |
| 4 | Adding sorafenib enhanced the NK sensitivity of HCC cells via increased expression of membrane-bound MICA. | Sorafenib | MHC class I polypeptide-related sequence A | Homo sapiens |