Title : Carboxymethylated tetrahydropyridoindoles as aldose reductase inhibitors: in vitro selectivity study in intact rat erythrocytes in relation to glycolytic pathway.

Pub. Date : 2009 Dec

PMID : 20097954






1 Functional Relationships(s)
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1 Recently, novel carboxymethylated pyridoindoles, structural analogues of the efficient chain-breaking antioxidant stobadine, were designed, synthesised and characterised as prospective aldose reductase inhibitors endowed with antioxidant activity. dicarbine aldo-keto reductase family 1 member B1 Rattus norvegicus