Title : The NRF2-heme oxygenase-1 system modulates cyclosporin A-induced epithelial-mesenchymal transition and renal fibrosis.

Pub. Date : 2010 Apr 15

PMID : 20096777






1 Functional Relationships(s)
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1 Pretreatment of rat tubular epithelial NRK-52E cells with sulforaphane, an activator of NRF2, could prevent EMT gene changes such as the loss of E-cadherin and the increase in alpha-smooth muscle actin (alpha-SMA) expression. sulforaphane cadherin 1 Rattus norvegicus