Title : Xenon is an inhibitor of tissue-plasminogen activator: adverse and beneficial effects in a rat model of thromboembolic stroke.

Pub. Date : 2010 Apr

PMID : 20087367






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Xenon is an inhibitor of tissue-plasminogen activator: adverse and beneficial effects in a rat model of thromboembolic stroke. Xenon plasminogen activator, tissue type Rattus norvegicus
2 Because the active site of serine proteases is structurally conserved, we have hypothesized and investigated whether xenon may alter the catalytic efficiency of tissue-type plasminogen activator (tPA), a serine protease that is the only approved therapy for acute ischemic stroke today. Xenon plasminogen activator, tissue type Rattus norvegicus