Pub. Date : 2010 Apr
PMID : 20079473
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | On the other hand, IP6 markedly increased protein and mRNA levels of osteopontin, a potent inhibitor of crystal growth and matrix mineralization. | Phytic Acid | secreted phosphoprotein 1 | Homo sapiens |
| 2 | In summary, IP6 inhibits mineralization of osteoblast cultures by binding to growing crystals through negatively charged phosphate groups and by induction of inhibitory osteopontin expression. | Phytic Acid | secreted phosphoprotein 1 | Homo sapiens |
| 3 | These data suggest that IP6 may regulate physiologic bone mineralization by directly acting extracellularly, and by serving as a specific signal at the cellular level for the regulation of osteopontin gene expression. | Phytic Acid | secreted phosphoprotein 1 | Homo sapiens |