Title : WNT1-inducible signaling pathway protein-1 activates diverse cell survival pathways and blocks doxorubicin-induced cardiomyocyte death.

Pub. Date : 2010 May

PMID : 20074638






1 Functional Relationships(s)
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1 Here we show that in adult mouse cardiomyocytes, DOX activates (i) the pro-apoptotic p53, (ii) p38MAPK and JNK, (iii) Bax translocation, (iv) cytochrome c release, and (v) caspase 3. Doxorubicin BCL2-associated X protein Mus musculus