Title : Propofol protects rat astroglial cells against tert-butyl hydroperoxide-induced cytotoxicity; the effect on histone and cAMP-response-element-binding protein (CREB) signalling.

Pub. Date : 2009 Dec

PMID : 20065498






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 tBHP induced limited cytotoxicity, increased apoptosis, decreased glutamine synthetase and enolase activities, decreased nuclear CREB, CREB-P and histone proteins but unchanged cytosolic CREB and histone acetyltransferase (HDAC) expression. tert-Butylhydroperoxide cAMP responsive element binding protein 1 Rattus norvegicus
2 tBHP induced limited cytotoxicity, increased apoptosis, decreased glutamine synthetase and enolase activities, decreased nuclear CREB, CREB-P and histone proteins but unchanged cytosolic CREB and histone acetyltransferase (HDAC) expression. tert-Butylhydroperoxide cAMP responsive element binding protein 1 Rattus norvegicus
3 tBHP induced limited cytotoxicity, increased apoptosis, decreased glutamine synthetase and enolase activities, decreased nuclear CREB, CREB-P and histone proteins but unchanged cytosolic CREB and histone acetyltransferase (HDAC) expression. tert-Butylhydroperoxide cAMP responsive element binding protein 1 Rattus norvegicus