Title : Oxidant conditioning protects cartilage from mechanically induced damage.

Pub. Date : 2010 Jul

PMID : 20058262






1 Functional Relationships(s)
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1 Catalase, hypoxia-inducible factor-1alpha (HIF-1alpha), and glyceraldehyde 6-phosphate dehydrogenase (GAPDH) were significantly increased relative to untreated controls in explants treated four times with 100 microM tBHP, a regime that also resulted in a significant decrease in matrix metalloproteinase-3 (MMP-3) expression. tert-Butylhydroperoxide hypoxia inducible factor 1 subunit alpha Homo sapiens