Title : Granulocyte-macrophage colony-stimulating factor induces transcriptional activation of Egr-1 in murine peritoneal macrophages.

Pub. Date : 1991 Mar 25

PMID : 2005129






1 Functional Relationships(s)
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1 Endogenous protein kinase C activity in macrophages was depleted by treatment with 12-O-tetradecanoylphorbol-13-acetate for 24 h. GM-CSF increased Egr-1 mRNA in protein kinase C-depleted macrophages, whereas the stimulatory effect of 12-O-tetradecanoylphorbol-13-acetate on Egr-1 was blocked. Tetradecanoylphorbol Acetate early growth response 1 Mus musculus