Title : Chemopreventive response of diclofenac, a non-steroidal anti-inflammatory drug in experimental carcinogenesis.

Pub. Date : 2009 Nov-Dec

PMID : 20049376






3 Functional Relationships(s)
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1 The chemopreventive response was evaluated of nonsteroidal anti-inflammatory drug, Diclofenac, a preferential cyclooxygenase-2 (COX-2) inhibitor in 1,2-dimethyhydrazine (DMH)-induced colon cancer in rat model. 1,2-Dimethylhydrazine prostaglandin-endoperoxide synthase 2 Rattus norvegicus
2 The chemopreventive response was evaluated of nonsteroidal anti-inflammatory drug, Diclofenac, a preferential cyclooxygenase-2 (COX-2) inhibitor in 1,2-dimethyhydrazine (DMH)-induced colon cancer in rat model. 1,2-Dimethylhydrazine prostaglandin-endoperoxide synthase 2 Rattus norvegicus
3 A very high expression of COX-2 was seen in the colonic epithelium of DMH-treated rats, as analyzed by immunohistochemistry. 1,2-Dimethylhydrazine prostaglandin-endoperoxide synthase 2 Rattus norvegicus