Title : A single amino acid residue, Ala 105, confers 16alpha-hydroxylase activity to human cytochrome P450 17alpha-hydroxylase/17,20 lyase.

Pub. Date : 2010 Apr

PMID : 20043997






1 Functional Relationships(s)
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Protein Name
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1 In adrenal steroidogenesis, CYP17 catalyses the 17alpha-hydroxylation of pregnenolone and progesterone and the subsequent 17,20-lyase reaction, yielding adrenal androgens. Pregnenolone cytochrome P450 family 17 subfamily A member 1 Homo sapiens