Title : Regulation of phagocyte NADPH oxidase by hydrogen peroxide through a Ca(2+)/c-Abl signaling pathway.

Pub. Date : 2010 Mar 15

PMID : 20043988






1 Functional Relationships(s)
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1 In conclusion, H(2)O(2) stimulates NOX2-mediated superoxide generation in neutrophils and K562/NOX2 cells via a signaling pathway involving Ca(2+) influx and c-Abl tyrosine kinase acting upstream of PKCdelta. Superoxides ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens