Title : Role of growth factor receptor transactivation in high glucose-induced increased levels of Gq/11alpha and signaling in vascular smooth muscle cells.

Pub. Date : 2010 Aug

PMID : 20036247






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1 Furthermore, high glucose-induced enhanced levels of Gqalpha, G11alpha and PLCbeta were also attenuated by PD98059, an inhibitor of mitogen-activated protein kinase (MAPK) and wortmannin, an inhibitor of phosphatidylinositol 3-kinase (PI3-K). Wortmannin phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Homo sapiens