Title : Repetitive self-grooming behavior in the BTBR mouse model of autism is blocked by the mGluR5 antagonist MPEP.

Pub. Date : 2010 Mar

PMID : 20032969






1 Functional Relationships(s)
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1 Methyl-6-phenylethynyl-pyridine (MPEP), an antagonist of the mGluR5 metabotropic glutamate receptor, blocks aberrant phenotypes in the Fmr1 mouse model of Fragile X, a comorbid neurodevelopmental disorder with autistic features. MPEP fragile X messenger ribonucleoprotein 1 Mus musculus