Pub. Date : 2010 Jan 30
PMID : 20006625
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Furthermore, reduction of NFkappaB binding capacity demonstrated by EMSA and ChIP assay suggested that NFkappaB plays an important role in bortezomib suppressing FAK expression. | Bortezomib | nuclear factor kappa B subunit 1 | Homo sapiens |
| 2 | Furthermore, reduction of NFkappaB binding capacity demonstrated by EMSA and ChIP assay suggested that NFkappaB plays an important role in bortezomib suppressing FAK expression. | Bortezomib | nuclear factor kappa B subunit 1 | Homo sapiens |
| 3 | SIGNIFICANCE: These results suggested that FAK is downregulated by bortezomib through a proteasome-dependent NFkappaB inhibitory mechanism. | Bortezomib | nuclear factor kappa B subunit 1 | Homo sapiens |