Title : Effect of pioglitazone on insulin resistance in fructose-drinking rats correlates with AGEs/RAGE inhibition and block of NADPH oxidase and NF kappa B activation.

Pub. Date : 2010 Mar 10

PMID : 20004657






1 Functional Relationships(s)
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1 Furthermore, we found that the expression of p47phox component of NAPDH oxidase, phosphorylated nuclear factor NF-kappaB p65, tumor necrosis factor alpha and interleukin-1 beta was significantly increased in the cerebral cortex of fructose-drinking rats (P<0.001). Fructose tumor necrosis factor Rattus norvegicus