Title : Increased immunogenicity of surviving tumor cells enables cooperation between liposomal doxorubicin and IL-18.

Pub. Date : 2009 Dec 10

PMID : 20003308






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1 CONCLUSION: These data demonstrate that Doxil favorably changes the immunophenotype of a large fraction of the tumor that escapes direct killing thus creating an opportunity to expand tumor killing by immunotherapy, which can be capitalized through addition of IL-18 in vivo. liposomal doxorubicin interleukin 18 Mus musculus