Title : Antiangiogenic drugs in oncology: a focus on drug safety and the elderly - a mini-review.

Pub. Date : 2010

PMID : 19940466






1 Functional Relationships(s)
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1 Sunitinib, a small molecule blocking intracellular VEGF, KIT, Flt3 and PDGF receptors, which regulate angiogenesis and cell growth, is approved for the treatment of advanced renal cell cancer (RCC) and malignant gastrointestinal stromal tumor. Sunitinib fms related receptor tyrosine kinase 3 Homo sapiens