Title : Structural determinants of the high affinity extracellular zinc binding site on Cav3.2 T-type calcium channels.

Pub. Date : 2010 Jan 29

PMID : 19940152






2 Functional Relationships(s)
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1 Ca(v)3.2 T-type channels contain a high affinity metal binding site for trace metals such as copper and zinc. Metals immunoglobulin lambda variable 7-43 Homo sapiens
2 A histidine at position 191 was recently identified as a critical determinant for both trace metal block of Ca(v)3.2 and modulation by redox agents. Metals immunoglobulin lambda variable 7-43 Homo sapiens