Title : The XPA-binding domain of ERCC1 is required for nucleotide excision repair but not other DNA repair pathways.

Pub. Date : 2010 Feb 5

PMID : 19940136






1 Functional Relationships(s)
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1 Mutation of two conserved residues (Asn-110 and Tyr-145) located in the XPA-binding site of ERCC1 dramatically affected NER but not nuclease activity on model DNA substrates. Tyrosine XPA, DNA damage recognition and repair factor Homo sapiens