Title : Evidence of a specific interaction between new synthetic antisepsis agents and CD14.

Pub. Date : 2009 Dec 29

PMID : 19928913






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Molecules that inhibited TLR4 activation inhibited LBP.CD14-dependent transfer of endotoxin monomers derived from aggregates of tritiated lipooligosaccharide ([(3)H]LOS) from Neisseria meninigitidis to MD-2.TLR4, resulting in a reduced level of formation of a ([(3)H]LOS.MD-2.TLR4(ECD))(2) (M(r) approximately 190000) complex. lipid-linked oligosaccharides CD14 molecule Homo sapiens