Title : Aryl hydrocarbon receptor regulates cell cycle progression in human breast cancer cells via a functional interaction with cyclin-dependent kinase 4.

Pub. Date : 2010 Feb

PMID : 19917880






1 Functional Relationships(s)
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1 In vitro assays for CDK4 kinase activity demonstrated that RB1 phosphorylation by the AHR/CDK4/CCND1 complex was reduced in the presence of TCDD. Polychlorinated Dibenzodioxins RB transcriptional corepressor 1 Homo sapiens