Title : C-Raf inhibits MAPK activation and transformation by B-Raf(V600E).

Pub. Date : 2009 Nov 13

PMID : 19917255






1 Functional Relationships(s)
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1 Moreover, both oncogenic Ras and Sorafenib stabilize B-Raf(V600E)-C-Raf complexes, thereby impairing MAPK activation. Sorafenib B-Raf proto-oncogene, serine/threonine kinase Homo sapiens