Title : The potential of lactate and succinate to kill nutrient deprived tumor cells by intracellular acidification.

Pub. Date : 1991 Feb

PMID : 1991688






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 Each of the three substances caused a decrease of intracellular pH (pHi) when the cell lines were exposed at low extracellular pH (pHe) in the range 6.0-6.5. Phenylalanine glucose-6-phosphate isomerase Homo sapiens
2 The fall in pHi increased with increasing dose of each agent and with decreasing pHe. Phenylalanine glucose-6-phosphate isomerase Homo sapiens