Title : Endogenous IL-21 restricts CD8+ T cell expansion and is not required for tumor immunity.

Pub. Date : 2009 Dec 1

PMID : 19915059






1 Functional Relationships(s)
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1 We found intact immune surveillance toward methylcholanthrene-induced sarcomas in IL-21(-/-) and IL-21R(-/-) mice compared with wild-type mice and B16 melanomas showed equal growth kinetics and development of lung metastases. Methylcholanthrene interleukin 21 Mus musculus