Pub. Date : 2010 Jan 1
PMID : 19914207
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We recently characterized iron-dependent toxic alpha-syn oligomer species by confocal single molecule fluorescence techniques and used this aggregation model to identify several N"-benzylidene-benzohydrazide (NBB) derivatives inhibiting oligomer formation in vitro. | N-butylbenzenesulfonamide | synuclein alpha | Homo sapiens |
| 2 | Similar to our previous findings in vitro, we found a converse modulation of toxic alpha-syn oligomers by NBB derivates and ferric iron, which was characterized by an increase in aggregate formation by iron and an inhibitory effect of certain NBB compounds. | N-butylbenzenesulfonamide | synuclein alpha | Homo sapiens |
| 3 | Similar to our previous findings in vitro, we found a converse modulation of toxic alpha-syn oligomers by NBB derivates and ferric iron, which was characterized by an increase in aggregate formation by iron and an inhibitory effect of certain NBB compounds. | N-butylbenzenesulfonamide | synuclein alpha | Homo sapiens |