Pub. Date : 2010 Feb
PMID : 19903832
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | 15-hydroxyeicosatetraenoic acid is a preferential peroxisome proliferator-activated receptor beta/delta agonist. | Eicosatetraenoic acid, 15-hydroxy- | peroxisome proliferator activated receptor delta | Homo sapiens |
| 2 | Here, we report that the AA metabolite 15-hydroxyeicosatetraenoic acid (15-HETE) activates the ligand-dependent activation domain (AF2) of PPARbeta/delta in vivo, competes with synthetic agonists in a PPARbeta/delta ligand binding assay in vitro, and triggers the interaction of PPARbeta/delta with coactivator peptides. | Eicosatetraenoic acid, 15-hydroxy- | peroxisome proliferator activated receptor delta | Homo sapiens |
| 3 | Here, we report that the AA metabolite 15-hydroxyeicosatetraenoic acid (15-HETE) activates the ligand-dependent activation domain (AF2) of PPARbeta/delta in vivo, competes with synthetic agonists in a PPARbeta/delta ligand binding assay in vitro, and triggers the interaction of PPARbeta/delta with coactivator peptides. | Eicosatetraenoic acid, 15-hydroxy- | peroxisome proliferator activated receptor delta | Homo sapiens |
| 4 | Here, we report that the AA metabolite 15-hydroxyeicosatetraenoic acid (15-HETE) activates the ligand-dependent activation domain (AF2) of PPARbeta/delta in vivo, competes with synthetic agonists in a PPARbeta/delta ligand binding assay in vitro, and triggers the interaction of PPARbeta/delta with coactivator peptides. | Eicosatetraenoic acid, 15-hydroxy- | peroxisome proliferator activated receptor delta | Homo sapiens |