Pub. Date : 2010 Jan
PMID : 19883715
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Lineweaver-Burk plot analysis indicated that apigenin and its dimer amentoflavone and imperatorin displayed a mixed type of inhibition on CYP3A4 or CYP2C9. | amentoflavone | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |
| 2 | Among the inhibitors, amentoflavone was the most potent inhibitor of CYP3A4 and CYP2C9 activities with IC(50) values of 0.07 and 0.03 microM, respectively. | amentoflavone | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |
| 3 | The K(i) value of amentoflavone was significantly lower than that of the CYP2C9 inhibition positive control sulfaphenazole. | amentoflavone | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |