Title : THE MECHANISM OF ENZYME-INHIBITOR-SUBSTRATE REACTIONS : ILLUSTRATED BY THE CHOLINESTERASE-PHYSOSTIGMINE-ACETYLCHOLINE SYSTEM.

Pub. Date : 1944 Jul 20

PMID : 19873399






5 Functional Relationships(s)
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1 THE MECHANISM OF ENZYME-INHIBITOR-SUBSTRATE REACTIONS : ILLUSTRATED BY THE CHOLINESTERASE-PHYSOSTIGMINE-ACETYLCHOLINE SYSTEM. Physostigmine butyrylcholinesterase Homo sapiens
2 The inhibition of cholinesterase by physostigmine is competitive. Physostigmine butyrylcholinesterase Homo sapiens
3 A single molecule of physostigmine or acetylcholine combines with one center of cholinesterase-n = 1; and the mechanism n = 2 has been. Physostigmine butyrylcholinesterase Homo sapiens
4 The destruction of physostigmine or acetylcholine by cholinesterase follows the predicted curve; k(D) for the destruction of physostigmine is found to be > 0.00182; k(D) for acetylcholine destruction is > 3500. Physostigmine butyrylcholinesterase Homo sapiens
5 The destruction of physostigmine or acetylcholine by cholinesterase follows the predicted curve; k(D) for the destruction of physostigmine is found to be > 0.00182; k(D) for acetylcholine destruction is > 3500. Physostigmine butyrylcholinesterase Homo sapiens