Title : TNF-alpha-mediated reduction in PGC-1alpha may impair skeletal muscle function after cigarette smoke exposure.

Pub. Date : 2010 Feb

PMID : 19859910






1 Functional Relationships(s)
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1 In this study cigarette smoke exposure was hypothesized to increase expression of the inflammatory cytokine, TNF-alpha, thereby suppressing PGC-1alpha, and hence affecting down stream molecules that regulate oxygen transport and muscle function. Oxygen tumor necrosis factor Mus musculus