Title : Alterations in skin immune response throughout chronic UVB irradiation-skin cancer development and prevention by naproxen.

Pub. Date : 2010 Jan-Feb

PMID : 19845543






4 Functional Relationships(s)
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1 Prostaglandin E(2) (PGE(2)) and tumor necrosis factor alpha (TNF-alpha) levels were increased 96 h post-UVB in acutely irradiated animals and both mediators were modified by topical naproxen application-PGE(2) was decreased while TNF-alpha was increased. Naproxen tumor necrosis factor Mus musculus
2 Prostaglandin E(2) (PGE(2)) and tumor necrosis factor alpha (TNF-alpha) levels were increased 96 h post-UVB in acutely irradiated animals and both mediators were modified by topical naproxen application-PGE(2) was decreased while TNF-alpha was increased. Naproxen tumor necrosis factor Mus musculus
3 Prostaglandin E(2) (PGE(2)) and tumor necrosis factor alpha (TNF-alpha) levels were increased 96 h post-UVB in acutely irradiated animals and both mediators were modified by topical naproxen application-PGE(2) was decreased while TNF-alpha was increased. Naproxen tumor necrosis factor Mus musculus
4 Furthermore, reduction in the incidence of tumor lesions by naproxen may be due to its ability to increase TNF-alpha levels as well as to decrease PGE(2). Naproxen tumor necrosis factor Mus musculus