Title : In vitro and in vivo evaluation of the inhibition potential of risperidone toward clozapine biotransformation.

Pub. Date : 2009 Oct

PMID : 19843060






1 Functional Relationships(s)
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1 RESULTS: (i) The CYP3A4 and CYP1A2 inhibitors ketoconazole and fluvoxamine inhibited CLZ oxidation to varying extents in individual microsomal fractions. Fluvoxamine cytochrome P450 family 3 subfamily A member 4 Homo sapiens