Pub. Date : 2009
PMID : 19827268
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Resveratrol downregulates PI3K/Akt/mTOR signaling pathways in human U251 glioma cells. | Resveratrol | mechanistic target of rapamycin kinase | Homo sapiens |
| 2 | In the current studies, the effect of resveratrol on phosphoinositide kinase-3 (PI3K)/protein kinase B (Akt)/mammalian target of rapamycin (mTOR) signaling pathway was examined in human U251 glioma cells. | Resveratrol | mechanistic target of rapamycin kinase | Homo sapiens |
| 3 | In the current studies, the effect of resveratrol on phosphoinositide kinase-3 (PI3K)/protein kinase B (Akt)/mammalian target of rapamycin (mTOR) signaling pathway was examined in human U251 glioma cells. | Resveratrol | mechanistic target of rapamycin kinase | Homo sapiens |
| 4 | Resveratrol reduced phosphorylation of ribosomal protein S6 and the mTOR inhibitor rapamycin further enhanced resveratrol-induced cell death. | Resveratrol | mechanistic target of rapamycin kinase | Homo sapiens |
| 5 | These results suggest that the downregulation of PI3K/Akt/mTOR signaling pathways may be an important mediator in resveratrol-induced apoptosis in glioma cells. | Resveratrol | mechanistic target of rapamycin kinase | Homo sapiens |