Title : Identification of WEE1 as a potential molecular target in cancer cells by RNAi screening of the human tyrosine kinome.

Pub. Date : 2010 Jul

PMID : 19821025






1 Functional Relationships(s)
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Compound Name
Protein Name
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1 RNAi-mediated silencing or small compound inhibition of WEE1 in breast cancer cell lines resulted in an increase in gammaH2AX levels, arrest in the S-phase of the cell cycle, and a significant decrease in cell proliferation. gammah2ax WEE1 G2 checkpoint kinase Homo sapiens